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Excessive MDA in liver tissue will consume a large amount of antioxidative factors, such as SOD and GSH, which can protect liver from the attacks of free radicals, but once the balance is broken, SOD and GSH will be unable to protect liver against the excessively increased MDA (22,23)

The numbers of lesions per mouse also differed as a function of diet, with recipients of CD and HFD showing 2.140.40 and 1.170.17 lesions, respectively

The average intake per animal was used to calculate feed conversion efficiency (average weight gain per cage 100/average food intake per cage)

10.1038/s41418-019-0304-y Cell Death Differ

In a randomised, double-blind, placebo-controlled, crossover trial (NCT04463030), liposomal vitamin C significantly improved plasma ascorbate and cellular antioxidant protection at 2 h post-consumption, which remained elevated at 6 h compared with placebo and regular vitamin C